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Chen and colleagues have proposed to use melatonin coupled to magnetite (Fe 3 O 4 ) nanobeads for a controlled sequential drug release, thereby relying on the finding that pure Fe 3 O 4 nanobeads had promoted peripheral nerve regeneration (Chen X

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The CUD participants were recruited in this ancillary study from a wider sample of treatment-seeking patients participating in the Brainswitch project, a double-blind, sham-controlled trial testing the ability of repetitive transcranial magnetic stimulation to treat CUD (preliminary data published in Martinotti et al